Impact by Design: Care Gaps & TPO Methodology in Medical Affairs

Medical Affairs teams have spent years talking about impact. The harder question is how to build the systems, goals, and accountability structures that make impact repeatable rather than aspirational.

Troels Sørensen (Global Head of Clinical Practice, Boehringer Ingelheim) and Scott Thompson (CEO, Acceleration Point) walk Medical Affairs leaders through the practical application of care gap analysis and Target Population Output (TPO) methodology to real-world patient journeys. They cover how to define and quantify meaningful care gaps, translate them into TPOs and stakeholder indicators, set accountability-based goals without creating fear, and build the organizational scaffolding, roles, processes, routines, that turns methodology into how the team actually works. More than 62 questions came in from Medical Affairs leaders before and during the live session, and Troels and Scott address the implementation realities, edge cases, and compliance boundaries teams are navigating right now. If your organization is ready to move from impact talk to impact habits, this is the session to watch.

What You'll Learn

• How to define and quantify care gaps using a logic model framework tied to real-world patient journeys
• What a Target Population Output (TPO) is, how it differs from a care gap, and how to express patient progress as a percentage for compliant commercial alignment
• How to prioritize care gaps when data is imperfect, incomplete, or inconsistent
• The compliance guardrails that determine which TPOs Medical Affairs can own, and why attribution is the wrong goal
• How Field Medical and MSL teams apply TPO accountability in daily practice
• The organizational scaffolding required for adoption: roles, processes, goals, and reward systems

About Our Speakers

Troels Sørensen is Global Head of Clinical Practice at Boehringer Ingelheim, where he leads Medical Affairs Partnerships and Implementation Science. He has worked across organizations, including Roche, AstraZeneca, and Novartis, applying TPO methodology, quantified patient journeys, and logic models to measure whether health-system interventions are changing patient outcomes. His approach has been recognized and built upon by the Harvard Health System Innovation Lab.

Connect with Troels on LinkedIn: https://www.linkedin.com/in/troelssorensen/

Scott Thompson is CEO at Acceleration Point, where he works with Medical Affairs and Field Medical leaders on operational strategy, impact measurement, and organizational infrastructure.

Connect with Scott on LinkedIn: https://www.linkedin.com/in/scottthompsonap/

About Acceleration Point Webinars

Acceleration Point webinars bring Medical Affairs and Field Medical leaders together to share practical insights, emerging strategies, and real-world perspectives on the challenges shaping the industry. Each session is designed to support the professionals driving scientific exchange, field medical excellence, and Medical Affairs transformation.

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